糖皮质激素抵抗机制的研究近况(4)
[21] Hawkins GA，Lazarus R，Smith RS，et al.The glucocorticoid receptor heterocomplex gene STIP1 is associated with improved lung function in asthmatic subjects treated with inhaled corticosteroids[J].J Allergy Clin Immunol，2009，123(6)：1376-1383.
[22] van den Akker EL，Russcher H，van Rossum EF，et al.Glucocorticoid receptor polymorphism affects transrepression but not transactivation[J].J Clin Endocrinol Metab，2006，91(7)：2800-2803.
[23] Hillmann AG，Ramdas J，Multanen K，et al.Glucocorticoid receptor gene mutations in leukemic cells acquired in vitro and in vivo[J].Cancer Res，2000，60(7)：2056-2062.
[24] Irving JA，Minto L，Bailey S，et al.Loss of heterozygosity and somatic mutations of the glucocorticoid receptor gene are rarely found at relapse in pediatric acute lymphoblastic leukemia but may occur in a subpopulation early in the disease course[J].Cancer Res，2005，65(21)：9712-9718.
[25] Charmandari E，Raji A，Kino T，et al.A novel point mutation in the ligand-binding domain (LBD) of the human glucocorticoid receptor (hGR) causing generalized glucocorticoid resistance：the importance of the C terminus of hGR LBD in conferring transactivational activity[J].J Clin Endocrinol Metab，2005，90(6)：3696-3705.
[26] Kotani A，Ha D，Schotte D，et al.A novel mutation in the miR-128b gene reduces miRNA processing and leads to glucocorticoid resistance of MLL-AF4 acute lymphocytic leukemia cells[J].Cell Cycle，2010，9(6)：1037-1042., 百拇医药(梁燕)
[22] van den Akker EL，Russcher H，van Rossum EF，et al.Glucocorticoid receptor polymorphism affects transrepression but not transactivation[J].J Clin Endocrinol Metab，2006，91(7)：2800-2803.
[23] Hillmann AG，Ramdas J，Multanen K，et al.Glucocorticoid receptor gene mutations in leukemic cells acquired in vitro and in vivo[J].Cancer Res，2000，60(7)：2056-2062.
[24] Irving JA，Minto L，Bailey S，et al.Loss of heterozygosity and somatic mutations of the glucocorticoid receptor gene are rarely found at relapse in pediatric acute lymphoblastic leukemia but may occur in a subpopulation early in the disease course[J].Cancer Res，2005，65(21)：9712-9718.
[25] Charmandari E，Raji A，Kino T，et al.A novel point mutation in the ligand-binding domain (LBD) of the human glucocorticoid receptor (hGR) causing generalized glucocorticoid resistance：the importance of the C terminus of hGR LBD in conferring transactivational activity[J].J Clin Endocrinol Metab，2005，90(6)：3696-3705.
[26] Kotani A，Ha D，Schotte D，et al.A novel mutation in the miR-128b gene reduces miRNA processing and leads to glucocorticoid resistance of MLL-AF4 acute lymphocytic leukemia cells[J].Cell Cycle，2010，9(6)：1037-1042., 百拇医药(梁燕)