不同孕期PT、APTT、FIB、INR四项血凝指标的变化(2)
因此，本文認为随着孕期的增加体内血液呈高凝状态，检测孕妇凝血功能指标对保证孕产妇及围生儿健康有重要意义。
参考文献
[1]王秀华.临产孕妇凝血指标和血小板参数的变化及其临床意义[J].临床医学，2013，33(5)：31-32.
[2]王永平，李琳，唐伟.临产孕妇凝血指标及血小板参数测定的临床意义[J].检验医学与临床，2012，9(24)：3064-3065.
[3] Shakhbazov S G.The changes of the main indices of theblood coagulation system in pregnant women with thrombotic complications[J].Klin Khir，2014，15(4)：47.
[4] Dusse L M，Carvalho M G，Cooper A J，et al.Tissue factorand tissue factor pathway inhibitor：a potential role in pregnancy and obstetric vascular complications[J].Clin Chim Acta，2013，372(12)：43.
[5] Cerneca F，Ricci G，Simeone R，et al.Coagulation and fi-brinolysis changes in normal pregnancy.Increased levels of procoagulants and reduced levels of inhibitors duringpregnancy inducea hypercoa gulablestate，combined witha reactive fibrinolysis[J].Eur J Obstet Gynecol Reprod Biol，2014，73(12)：31-36.
[6] Morikawa M，Yamada T.Changes in antithrombin activity and platelet counts in the late stage of twin and triplet pregnancies[J].Semin-Thromb-Hemost，2013，31(3)：290-296.
[7] Saino S，Kekomak R.Maternal thrombocytopenia at term：a population-based study[J].Acta-Obstet-Gynecol-Scand，2013，79(9)：744-749.
[8] Boehlen F.Importance，diagnosis andmanagement[J].Hamostaseologie，2013，26(1)：72-74.
[9] Minakami H，Yamada H.Gestational thrombocytopenia and pregnancy-induced antithrombin deficiency：progenitors to the development of the HELLP syndrome and acute fatty liver of pregnancy[J].Semin-Thromb-Hemost，2012，30(6)：515-518.
[10] Minakami H，Kohmura Y.Relation between gestational thrombocytopenia and the syndrome of hemolysis，elevated liver enzymes，and low platelet count(HELLP syndrome)[J].Gynecol-Obstet-Invest，2015，46(1)：41-45.
(收稿日期：2016-10-11), http://www.100md.com(王敏)
参考文献
[1]王秀华.临产孕妇凝血指标和血小板参数的变化及其临床意义[J].临床医学，2013，33(5)：31-32.
[2]王永平，李琳，唐伟.临产孕妇凝血指标及血小板参数测定的临床意义[J].检验医学与临床，2012，9(24)：3064-3065.
[3] Shakhbazov S G.The changes of the main indices of theblood coagulation system in pregnant women with thrombotic complications[J].Klin Khir，2014，15(4)：47.
[4] Dusse L M，Carvalho M G，Cooper A J，et al.Tissue factorand tissue factor pathway inhibitor：a potential role in pregnancy and obstetric vascular complications[J].Clin Chim Acta，2013，372(12)：43.
[5] Cerneca F，Ricci G，Simeone R，et al.Coagulation and fi-brinolysis changes in normal pregnancy.Increased levels of procoagulants and reduced levels of inhibitors duringpregnancy inducea hypercoa gulablestate，combined witha reactive fibrinolysis[J].Eur J Obstet Gynecol Reprod Biol，2014，73(12)：31-36.
[6] Morikawa M，Yamada T.Changes in antithrombin activity and platelet counts in the late stage of twin and triplet pregnancies[J].Semin-Thromb-Hemost，2013，31(3)：290-296.
[7] Saino S，Kekomak R.Maternal thrombocytopenia at term：a population-based study[J].Acta-Obstet-Gynecol-Scand，2013，79(9)：744-749.
[8] Boehlen F.Importance，diagnosis andmanagement[J].Hamostaseologie，2013，26(1)：72-74.
[9] Minakami H，Yamada H.Gestational thrombocytopenia and pregnancy-induced antithrombin deficiency：progenitors to the development of the HELLP syndrome and acute fatty liver of pregnancy[J].Semin-Thromb-Hemost，2012，30(6)：515-518.
[10] Minakami H，Kohmura Y.Relation between gestational thrombocytopenia and the syndrome of hemolysis，elevated liver enzymes，and low platelet count(HELLP syndrome)[J].Gynecol-Obstet-Invest，2015，46(1)：41-45.
(收稿日期：2016-10-11), http://www.100md.com(王敏)