氯吡格雷联合阿司匹林治疗短暂性脑缺血发作的疗效及安全性研究
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[摘要] 目的 探讨氯吡格雷联合阿司匹林在短暂性脑缺血发作中的疗效及安全性。 方法 选取60例TIA患者，随机分为两组，对照组予小剂量阿司匹林，观察组则在对照组予氯比格雷，比较两组的疗效及用药安全性。 结果 观察组总有效率达90.0%，与对照组的总有效率73.3%比较，差异有统计学意义(P<0.05)。观察组治疗后发作时间均较治疗前及对照组缩短更明显，差异有统计学意义(P<0.05)。 结论 氯吡格雷联合阿司匹林治疗短暂性脑缺血发作能明显减少发作时间，改善患者的临床症状，安全性好，值得推广和应用。
[关键词] 短暂性脑缺血发作；氯吡格雷；阿司匹林
[中图分类号] R743.31?[文献标识码] B?[文章编号] 2095-0616(2012)15-73-02
Efficacy and safety of clopidogrel and aspirin treatment of transient ischemic attack
GUO?Xinsheng?YI?Shihua
Department of Internal Medicine,Suichuan County People's Hospital,Suichuan 343900,China
[Abstract] Objective To explore efficacy and security of clopidogrel and aspirin in transient ischemic attack. Methods 60 patients with TIA were randomly divided into two groups,the low-dose aspirin in the control group. On the base of the control group,observation group were given clopidogrel,the efficacy and drug safety were compared between the two groups ......
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