胃间质瘤采用腹腔镜胃楔形切除术进行治疗的临床疗效及其安全性分析(1)
[摘要] 目的 探讨分析应用腹腔镜胃楔形切除术治疗胃间质瘤的临床疗效和安全性。 方法 选择我院收治的胃间质瘤患者120例作为研究对象，随机分为研究组和对照组，各60例。对照组均进行开腹胃楔形切除手术，研究组均进行腹腔镜胃楔形切除术。将两组患者的手术切口长度、术中出血量、术后排气时间、术后住院时间以及术后并发症发生情况进行对比。 结果 两组患者手术时间相近，差异无统计学意义(P>0.05)；研究组患者的手术切口长度、术中出血量、术后排气时间以及术后住院时间均显著少于对照组，差异均有统计学意义(P<0.05)。研究组患者并发症发生率为5.00%，显著低于对照组的30.00%，差异具有统计学意义(P<0.05)。 结论 应用腹腔镜胃楔形切除术治疗胃间质瘤，可以产生显著的临床效果，患者创伤小、恢复快，住院时间短，并发症发生率低，具有较高的安全性，值得推广应用。
[关键词] 胃间质瘤；楔形切除术；腹腔镜；开腹手术
[中图分类号] R735.2 [文献标识码] B [文章编号] 2095-0616(2015)18-93-03
, http://www.100md.com
[Abstract] Objective To explore the clinical efficacy and safety of stromal tumor resection for the treatment of gastric analysis application of laparoscopic gastric wedge. Methods In our hospital in patients with gastrointestinal stromal tumor in 120 cases as the research object，randomly divided into study group and control group，each of 60 cases.The control group underwent open gastric wedge resection operation，the study group were performed laparoscopic wedge resection of stomach.The incision length，operation of the two groups of patients with bleeding，postoperative exhaust time，postoperative hospital stay and postoperative complications were compared. Results The two groups of patients with operation time are similar，there was no significant difference (P>0.05)；Operation incision length，operation of the patients in the study groups in the amount of bleeding，postoperative exhaust time and postoperative hospital stay were significantly less than that in the control group，the difference was statistically significant (P<0.05).Study group the incidence of complications was 5.00%， significantly lower than the control group of 30.00%， with significant difference (P<0.05). Conclusion The application of laparoscopic gastric wedge resection in the treatment of gastric stromal tumor，can produce a significant clinical effect，small trauma，quick recovery，short hospitalization time，low complication rate，high security，and is worthy of popularization and application.
, 百拇医药
[Key words] Gastric stromal tumor；Wedge resection；Laparoscopy；Laparotomy
近年来，胃间质瘤具有较高的发病率，其发病比例约为消化道间叶肿瘤的60%～70%，严重影响患者健康和正常生活[1-2]。该病不仅可发生于全胃道，也可发生于胃道外部位。胃间质瘤具有一定的恶性潜能，应用常规的化学疗法以及放射疗法均无法取得较为满意的临床效果，临床上一般采取手术切除方法进行治疗，手术方法也是目前唯一有效的治疗方法[3]。随着近年来腹腔镜技术的长足发展，腹腔镜胃间质瘤楔形切除术己逐渐成为临床上治疗胃间质瘤的常用手术方式。我院积极开展该项研究，取得了显著的成效。具体情况如下。
1 资料与方法
1.1 一般资料
本研究选择2013年6月～2014年6月期间我院收治的胃间质瘤患者，共计120例。其中男86例，女34例；患者年龄19～75岁，平均(51.6±8.8)岁；在具体肿瘤部位方面，含胃体48例、胃底42例、胃窦30例；在Fletcher风险分级方面[4]，高度26例，中度21例，低度42例，极低度32例；肿瘤直径为1.2～6.5cm，平均(3.5±1.8)cm。所有患者均符合胃间质瘤临床诊断标准并经CT、超声内镜以及胃镜等检查手段确诊。在征得本院伦理委员会同意的前提下将患者平均分为研究组和对照组，各60例，均签署知情同意书。两组患者上述各方面数据差异无统计学意义(P>0.05)，具有可比性。, 百拇医药(江祖德 曹丽燕)
[关键词] 胃间质瘤；楔形切除术；腹腔镜；开腹手术
[中图分类号] R735.2 [文献标识码] B [文章编号] 2095-0616(2015)18-93-03
, http://www.100md.com
[Abstract] Objective To explore the clinical efficacy and safety of stromal tumor resection for the treatment of gastric analysis application of laparoscopic gastric wedge. Methods In our hospital in patients with gastrointestinal stromal tumor in 120 cases as the research object，randomly divided into study group and control group，each of 60 cases.The control group underwent open gastric wedge resection operation，the study group were performed laparoscopic wedge resection of stomach.The incision length，operation of the two groups of patients with bleeding，postoperative exhaust time，postoperative hospital stay and postoperative complications were compared. Results The two groups of patients with operation time are similar，there was no significant difference (P>0.05)；Operation incision length，operation of the patients in the study groups in the amount of bleeding，postoperative exhaust time and postoperative hospital stay were significantly less than that in the control group，the difference was statistically significant (P<0.05).Study group the incidence of complications was 5.00%， significantly lower than the control group of 30.00%， with significant difference (P<0.05). Conclusion The application of laparoscopic gastric wedge resection in the treatment of gastric stromal tumor，can produce a significant clinical effect，small trauma，quick recovery，short hospitalization time，low complication rate，high security，and is worthy of popularization and application.
, 百拇医药
[Key words] Gastric stromal tumor；Wedge resection；Laparoscopy；Laparotomy
近年来，胃间质瘤具有较高的发病率，其发病比例约为消化道间叶肿瘤的60%～70%，严重影响患者健康和正常生活[1-2]。该病不仅可发生于全胃道，也可发生于胃道外部位。胃间质瘤具有一定的恶性潜能，应用常规的化学疗法以及放射疗法均无法取得较为满意的临床效果，临床上一般采取手术切除方法进行治疗，手术方法也是目前唯一有效的治疗方法[3]。随着近年来腹腔镜技术的长足发展，腹腔镜胃间质瘤楔形切除术己逐渐成为临床上治疗胃间质瘤的常用手术方式。我院积极开展该项研究，取得了显著的成效。具体情况如下。
1 资料与方法
1.1 一般资料
本研究选择2013年6月～2014年6月期间我院收治的胃间质瘤患者，共计120例。其中男86例，女34例；患者年龄19～75岁，平均(51.6±8.8)岁；在具体肿瘤部位方面，含胃体48例、胃底42例、胃窦30例；在Fletcher风险分级方面[4]，高度26例，中度21例，低度42例，极低度32例；肿瘤直径为1.2～6.5cm，平均(3.5±1.8)cm。所有患者均符合胃间质瘤临床诊断标准并经CT、超声内镜以及胃镜等检查手段确诊。在征得本院伦理委员会同意的前提下将患者平均分为研究组和对照组，各60例，均签署知情同意书。两组患者上述各方面数据差异无统计学意义(P>0.05)，具有可比性。, 百拇医药(江祖德 曹丽燕)